Ccr2-2A-DreERT2

Nomenclature

C57BL/6Smoc-Ccr2em3(2A-DreERT2)Smoc

Cat. NO.

NM-KI-200023

Strain State

Sperm cryopreservation

Export PDF

Gene Summary

Gene Symbol
Ccr2

Synonyms

Ckr2; Ccr2a; Ccr2b; Ckr2a; Ckr2b; mJe-r; Cmkbr2; Cc-ckr-2

NCBI ID

12772

MGI ID

106185

Ensembl ID

ENSMUSG00000049103

Pubmed

Ccr2

Human Ortholog

CCR2

Model Description

A 2A-DreERT2 expression cassette was knocked into the Ccr2 gene stop codon site.
Research Application：Dre recombinase tool

Validation Data

image.png

Fig.1 DreERT2-mediated recombination in the liver of Ccr2DreERT2/+；R26tdTomato/+ mouse. TdTomato (red) expression can be detected in the liver after tamoxifen treatment. The F4/80 molecule is a unique marker of murine macrophages. (Documented in the following reference.)


Publications

A Suite of New Dre-recombinase Drivers Markedly Expands the Ability to Perform Intersectional Genetic Targeting
References：CELL STEM CELL

You may also like

Shanghai Model Organisms Center Inc has licensed CRISPR-Cas9 technology from Broad Institute

On Dec 16, 2018, Broad Institute and Shanghai Model Organisms Center Inc (SMOC) has entered into a non-exclusive license agreement under which Broad has granted SMOC worldwide rights to commercialize a service platform for genetically modified mouse models under Broad's intellectual property.

Learn more
Milestones

Our vision is to provide researchers all over the world with comprehensive, convenient and professional animal model services to facilitate a simplified and highly-efficient approach towards uncovering the mysteries of life.

Learn more