Pax7-2A-DreERT2

Nomenclature

C57BL/6Smoc-Pax7em1(2A-DreERT2)Smoc

Cat. NO.

NM-KI-190124

Strain State

Embryo cryopreservation

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Gene Summary

Gene Symbol
Pax7

Model Description

A 2A-DreERT2 expression cassette was knocked into the Pax7 gene stop codon site.
Research Application:Dre tool mouse

Validation Data

NM-KI-190124 Pax7-2A-DreERT2-1.png

Fig. 1 DreERT2-mediated recombination in the brain and muscle of Pax7DreERT2/+; Rosa26RFP/+ mouse. 

RFP+ cells (red) were colocalized with GFP+ cells (green) in the brain and muscle of Pax7DreERT2/+; Rosa26RFP/+ mouse after tamoxifen treatment. However, the expression of RFP by induced dre with Pax7DreERT2/+ was less effective in the muscle. (Collaborated with Prof. Zhou bin’s group from Center for Excellence in Molecular Cell Science, CAS)

NM-KI-190124 Pax7-2A-DreERT2-2.png

Fig. 2: Detection of RFP in various tissues of Pax7DreERT2/+; Rosa26RFP/+ mice. (For more detailed information please contact our technical advisor.) (Collaborated with Prof. Zhou bin’s group from Center for Excellence in Molecular Cell Science, CAS)



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