SMOC has developed a set of mouse models expressing humanized cytokines. These models are suitable to assess the efficacy of drugs targeting cytokines in fully immunocompetent mice.
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Strain Name：C57BL/6Smoc-Thpotm1(hTHPO)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000062
Research Application：Cytokine humanization model；drug screening
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Strain Name：C57BL/6Smoc-Tgtn(hTNFa promoter-hTNFa-pA)Smoc
Strain State：Repository Live | Cat. NO.：NM-TG-200004
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Strain Name：C57BL/6Smoc-Tnfsf13btm1(hTNFSF13B)Smoc
Strain State：Developing | Cat. NO.：NM-HU-200238
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Strain Name：C57BL/6Smoc-Tnfsf14tm1(hTNFSF14)Smoc
Strain State：Repository Live | Cat. NO.：NM-HU-225069
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Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-2000064
Research Application：Asthma research；drug screening
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Strain Name：C57BL/6Smoc-Tslptm2(hTSLP)Il17rtm1(hIL17R)/Smoc
Strain State：Embryo cryopreservation | Cat. NO.：NM-HU-200269
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Strain Name：C57BL/6Smoc-Gt(ROSA)26Sorem(CAG-Loxp-Stop-Loxp-Kozak-hIL2 signal peptide-hIL15-Flag-IRES-EGFP-polyA)Smoc
Strain State：Sperm cryopreservation | Cat. NO.：NM-KI-220130
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